6 Ways Your Body Is Losing Collagen

Being the most abundant protein in the body, collagen makes up 30% of the body’s protein and 70% of the skin’s protein. Because it’s so concentrated in the skin, its loss is detrimental to the skin’s health and a huge contributor to premature aging. 

Unfortunately, our collagen levels do decline for various reasons. This protein is crucial for not just your skin, but your bones, joints, muscle, cartilage, and more. As such, losing it is no joke. You want to avoid doing so as much as possible!

Today, I will go over the six main reasons we lose our collagen so that you can make mindful choices for your skin and overall health. 

1. UV Rays

We all love the sunshine, but the collagen in your skin? Not so much. 

UV rays from the sun can contribute to lower collagen levels in the skin. To demonstrate this, researchers placed collagen beneath a UV light and found that there was a significant drop in collagen structure afterwards. [1]

Additionally, harmful UV rays can cause free radicals, which in turn may destroy collagen, other structures of the skin, and cause inflammation. [2]

If you plan on spending a lot of time outside, be sure to wear sunscreen, cover up, or stick to the shade. Remember, if it’s daylight outside, the sun’s rays are out!

2. Smoking

Okay, we all know that smoking isn’t healthy, but some of us may still do it or be exposed to it through second-hand smoke. 

When it comes to ruining collagen, cigarettes are the big guns. Enemy number one. 

Smoking leads to premature aging in the skin. Tobacco triggers the production of a molecule called matrix metalloproteinases (MMP) which degrades collagen and other important dermal proteins. It also negatively impacts dermal connective tissue. [3]

One study which compared the skin and collagen levels of smokers and non-smokers found that collagen levels were 22% lower in those who smoked, and their MMP levels were 100% higher. [4]

Additionally, cigarettes cause a high level of free radicals to populate within the body, causing oxidative stress, which leads to damage in the skin and other organs. [5

If you smoke and you want to watch out for the health of your skin, quitting is probably the best thing you could do. If you don’t smoke, do your best to avoid second-hand smoke – especially regular or prolonged exposure.

3. Sugar

The more sugar in your diet, the worse off your skin is. 

Sugar causes elements of the skin to stiffen, reducing its elasticity. It cross links collagen fibers, damaging them. This damaging process is exacerbated if combined with UV ray exposure. [6]

When you’re already losing collagen in other ways, you don’t want to accelerate that by damaging the collagen you do have.

4. Stress

Stress affects the integrity of collagen, negatively impacting its production and contributing to degradation. [7

When we become stressed – regardless of why – our body releases stress hormones, namely cortisol. Cortisol on its own degrades collagen. On top of that, stress can cause inflammation to occur throughout the body and, like cortisol, inflammation damages our precious collagen. [8]

Similar to sugar, inflammation stiffens collagen, a process which can negatively impact the health of not just the skin, but several organs. [8]

5. Genetics

One thing that I did want to point out is that some of this may come down to genetics. 

If your parents and grandparents had great skin, then chances are that you will too. However, the opposite can be true as well.

It’s best, in my opinion, to be mindful of skin health and collagen levels regardless. But some of us may have to be more careful about it than others.

6. Aging

As we age, our body’s ability to synthesize collagen decreases. This decline begins in our 20s and, as a result, collagen levels decrease by 1% each year. [6]

Though the process of aging can’t be avoided, its effects can be mitigated. Depending on how many of the things in this article you’re exposed to, your collagen levels can decrease even faster. 

On the other hand, if you avoid them and take care of your skin, your collagen decline – and ergo skin aging – shouldn’t be nearly as drastic.

But there is another thing that you can do. 

If your body can’t make collagen, then why not give it collagen?

Supplementing can help you maintain collagen levels as you age, supporting the health of your skin, especially if you think you may be encountering any of the things on this list. 

But you need a form of collagen that your body can absorb.

>>> Click here to see why Complete Collagen Plus is superior to other collagens on the market

References and Resources

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299808/ 
  2. https://pubmed.ncbi.nlm.nih.gov/1333311/ 
  3. https://pubmed.ncbi.nlm.nih.gov/17951030/ 
  4. https://pubmed.ncbi.nlm.nih.gov/11966688/ 
  5. https://www.sciencedirect.com/science/article/abs/pii/S0891584917309814
  6. https://pubmed.ncbi.nlm.nih.gov/20620757/ 
  7. https://pubmed.ncbi.nlm.nih.gov/19523511/ 

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Parabens – What’s The Fuss?

If you’ve ever gone shopping for cosmetics, I’m guessing you’ve come across tons of products that are labelled as “paraben-free”. You’ve also likely encountered several products that still contain parabens. 

But why are some companies opting to leave out parabens? And what purpose do they serve in the first place?

To help you make a more informed decision about your cosmetics, I answer those questions and more in today’s article!

What are parabens?

Parabens are chemical compounds that have been used as a cosmetic preservative since the 1920s. Typically, you’ll find them in shampoos, body washes, and other water based products. The six most commonly used types of parabens are methyl-, ethyl-, propyl-, isopropyl-, butyl- and isobutylparaben. These can be used alone or in tandem. 

They’re effective at reducing or preventing the growth of mold or harmful bacteria, which helps keep products shelf stable for much longer. Moisturizers, face and skin cleaners, sunscreens, deodorants, shaving gels, toothpastes, makeup, and many other products can contain parabens. 

How does the body react to parabens?

Your skin absorbs parabens and then the body metabolizes them. From there, your body should excrete them. However, researchers are finding that this is not the case. Those who use products containing parabens tend to have them in their body at all times.

One study compared adolescent girls who wore makeup daily with girls who rarely or never wore makeup. Those who wore makeup every day had 20 times more parabens in their sample than the other group. Other studies have found similar results – an increased use of sunscreens, hair products, lotions, and makeup having a correlation to huge paraben counts within the body. [1, 2, 3, 4

Now, this may seem harmless if parabens were harmless. But the research is saying otherwise…

What are the health effects of parabens?

Surely, the occasional encounter with parabens would be harmless, and that’s the stance of many scientists in the field. But these are products you want to be using every day and without any health concerns. And this buildup of parabens in the body is reportedly causing some issues…

Reproductive harm – Certain parabens can act like the hormone estrogen in the body which can affect reproductive system functioning, reproductive development, fertility, and birth outcomes. 

Institutions such as The U.N. Environment Programme and The Danish Centre on Endocrine Disruptors have identified certain types of parabens as endocrine disruptors. [5, 6]

Studies have demonstrated parabens’ effects on estrogen. In animal studies, parabens harmed female reproductive development, male reproduction, and fertility. In humans, an increased paraben count in the body has been linked with reproductive issues and birth issues. [7, 8, 9, 10, 11, 12]  

Increase risk of cancer – Parabens have been found to alter the expression of genes and accelerate the growth of certain cancer cells. A 2016 study found that even small amounts of butylparaben may increase the growth of cancer cells. [13, 14, 15]

Skin irritation – On top of the internal issues, parabens have been found to irritate the skin over time. [16]

What can we do?

Parabens have been detected in infants, children, and adults. Parabens may also accumulate in fat tissue over time. [17, 18, 10, 19]

If you’ve been using products containing parabens, don’t stress. There are plenty of products out there without parabens that are ready to replace your paraben-filled cosmetics.

Remember the aforementioned study where the adolescent girls who used makeup every day had high amounts of parabens in their body? Well, after just three days of switching to paraben-free cosmetics, their paraben levels dropped by nearly 45%! [20]

Thankfully, parabens are easy to identify on product labels. Though there are many different types, they all end with “paraben”. When looking for cosmetics, do a check of the ingredient list. Make sure you’re getting products that are paraben-free and don’t contain any other harmful ingredients. 

After all, you’re going to be using these products routinely, and you don’t want them to be slowly harming you over time!

Complete Collagen+

Speaking of good ingredients, EverBella’s Micelle Liposomal Complete Collagen+ only includes all-natural ingredients. And every one of these natural ingredients has a job – meaning no filler!

If you want to add something to your daily regimen that will only benefit your health, Complete Collagen+ is a great choice.

Click here to see our ingredient list, reviews, and more.

And, as always, if you have any questions or concerns about EverBella, I want you to reach out!

Our team is available Mon-Fri between 9 a.m. and 5 p.m. EST for a call at 1-855-961-3837 or through email at info@everbella.com. We’d love to hear from you! 

References and Resources

  1. https://pubmed.ncbi.nlm.nih.gov/29317738/ 
  2. https://pubmed.ncbi.nlm.nih.gov/29524920/ 
  3. https://pubmed.ncbi.nlm.nih.gov/28886595/ 
  4. https://pubmed.ncbi.nlm.nih.gov/24149971/ 
  5. https://wedocs.unep.org/bitstream/handle/20.500.11822/25633/EDC_report1.pdf?sequence=1&isAllowed=y 
  6. https://cend.dk/files/DK_ED-list-final_2018.pdf 
  7. https://pubmed.ncbi.nlm.nih.gov/20132880/ 
  8. https://pubmed.ncbi.nlm.nih.gov/24607685/ 
  9. https://academic.oup.com/toxsci/article/152/1/244/2579219 
  10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855500/ 
  11. https://pubmed.ncbi.nlm.nih.gov/27189314/ 
  12. https://pubmed.ncbi.nlm.nih.gov/27156397/ 
  13. https://www.academia.edu/11169160/Actions_of_methyl-_propyl-and_butylparaben_on_estrogen_receptor-a_and_-b_and_the_progesterone_receptor_in_MCF-7_cancer_cells_and_non-cancerous_MCF-10A_cells 
  14. https://pubmed.ncbi.nlm.nih.gov/11696396/ 
  15. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858398/ 
  16. https://pubmed.ncbi.nlm.nih.gov/25395006/ 
  17. https://pubmed.ncbi.nlm.nih.gov/20056562/ 
  18. https://pubmed.ncbi.nlm.nih.gov/19440505/ 
  19. https://pubmed.ncbi.nlm.nih.gov/25749637/ 
  20. https://pubmed.ncbi.nlm.nih.gov/26947464/ 

6 Homemade Humidifier Ideas

Do you find that you’re much more prone to cracked hands, chapped lips, and dry skin this time of year?

The thing is, we run the heater more frequently in the winter (duh!) and that can suck the moisture right out of the air. It’s why you may wake up with a dry throat, headache, or even a bloody nose!

This dryness can even negatively affect your houseplants and furniture.

Buying a humidifier can help, but that can be costly. That’s why I wanted to share 6 DIY (Do It Yourself) humidifiers that you can use in your home to help with the dryness.

1. The Stovetop

This one works well to get moisture into the kitchen, or even the living/dining room if you have an open-concept layout. 

Add water to a kettle or pot and bring it to a boil on your stovetop. As the water boils, it will evaporate into steam and mix with the air of the room. 

Just be sure to keep your eye on it. The heat produced can cause burns if touched. Additionally, once the water evaporates completely, you could ruin your empty pot or kettle by keeping it on the heat.

Once finished, turn off the burner and let everything cool before handling.

2. Plants!

Plants need water, and if your home is too dry – depending on the plant – it could suffer as a result. So, not only could your plant’s health come as a warning, they can help you in another way.

When you water your plants, the water is taken up through the roots. But only about 3% of that water is used for growth and metabolism. The other 97% or so is released through the leaves as vapor by a process known as transpiration.

Just be sure to purchase plants that act as natural humidifiers, as some may have the opposite effect. Types of plants to look for are Areca Palm, Peace Lily, English Ivy, Rubber Plant, and Spider Plant.

It’s incremental, but every little bit helps!

On top of that, plants help keep the air fresh through photosynthesis and other processes that remove toxins from the air. They also lighten up your living space which contributes to happiness.

3. The Shower!

This one is killing two birds with one stone. When you shower with warm to hot water, steam is released into the air. Keep the bathroom fan off and open the door for your next shower. All of that steam will float out of the bathroom and add moisture to your home.

If you don’t want to shower with the door open, just open it when you’re done to let the moisture out.

If you’re really desperate, run the shower for a few minutes with the door open even if you’re not showering. Clog the drain and catch the water to use for another purpose to reduce waste.

4. The Heater

I know, I know – isn’t the heater what got us into this mess? But you can use it to your advantage!

This will vary depending on what type of heater you have, but placing a container of warm water on or by your heater can cause the water to evaporate, adding moisture to the air. For floor or wall vents, place a metal or ceramic container on or beside the vent. For wood-stoves or hot water radiators, place them right on top. 

Just be careful, these containers can become quite hot!

5. Not The Dryer

This one is a double whammy. Your clothes dryer is certainly convenient, but running it is only adding to your home’s dryness. 

Instead, take your wet clothes and hang them somewhere central in your home. As they dry, their moisture will seep out into the air. 

This way, you’re reducing the dryness that your dryer causes and adding moisture to the air.

6. The Sun!

Last but not least, you can use those warm sun rays that come through your window to your advantage. 

Grab a glass vase (or another large glass container), fill it with water, and place it by a window that catches the most amount of sunlight. As the sun beats down on it, the natural process of evaporation will take place, and the water will gradually turn to vapor, mixing in with the air in your home.

Just be sure to keep your eye on it and add water as needed!

Working From The Inside Out

Of course, keeping an environment that your skin agrees with is important. But so is giving your body the nutrients needed to help your skin be healthy in the first place.

One of these nutrients is collagen.

If you’ve noticed that your skin has a tougher time with each passing winter, it’s likely because our collagen levels drop as we age, and your skin is having difficulty keeping up.

Supplementing with an absorbable form of collagen can help you get the skin of your youth back. 

Click here to learn how Complete Collagen+ helped me (and how it can help you too)!

How To Care For Sensitive Skin

When it comes to skincare, there are some general things we can do. You know, the common advice – use lotions, avoid chemicals, stay hydrated. 

Of course, most of this works for all types of skin, including sensitive skin. But what things can we do for sensitive skin specifically?

Today I have some tips for those of us dealing with sensitive skin. Whether you’re having a breakout right now, or trying to avoid one in the future, this article is for you!

What is sensitive skin?

Sensitive skin can certainly fall onto a spectrum. You may not even know you have sensitive skin until it meets a certain cosmetic product or ingredient. Sensitive skin is usually a symptom of another condition and – in most cases – isn’t overly serious. But it can be uncomfortable and inconvenient. 

When your skin is overly sensitive, you want to be sure to take extra care of it. Otherwise, it could be a downward spiral.

For example, if your skin is overly dry, and it gets bothered by an ingredient or even more dried out, it can become itchy, inflamed, and aggravated. Then you’ve got a worse problem on your hands (joke intended, thank you). 

If you have an ongoing skin issue, such as chronic dryness, itchiness, bumps, rashes, or anything else that seems unusual and is persisting, don’t hesitate to see a doctor. In most cases, you may need a medical cream that can help your skin heal and get back to normal. There are a range of skin conditions that your doctor can help you pinpoint and treat. 

In the meantime, if you’re looking to take it easy on your skin or avoid another breakout altogether, keep reading!

How to care for sensitive skin

  • Take a short, lukewarm shower – You don’t need to be uncomfortable in the shower by any means. But if you’re taking a hot shower, that could be damaging your skin. If your skin appears redder when you leave the shower than it did when you got in, the water is too hot. And the longer you’re in there, the more you’re drying out your skin by removing its natural oils. 
  • Avoid harsh cosmetics – Many cosmetics have good intentions, but too many of them are made with ingredients that do your skin no favors. These ingredients could be to preserve the product or give it a certain texture. Be sure to read the ingredients and understand what each ingredient is and how they react with not just your skin, but each other.
  • Use gentle, fragrance-free soap – Soaps with a fragrance may smell nice, but even just the word “fragrance” on an ingredient list can be an umbrella term for a wide range of ingredients that you’re unaware of and are now putting on your skin.
  • Use a gentle laundry detergent – For the same reason as the above two points, you don’t want to be cooking your clothes in harmful chemicals and then having them rub up against your skin all day and night. Make sure you’re washing your clothes with clean ingredients!
  • Pat instead of rub – When you get out of the shower or finish washing your face, avoid rubbing the towel against your skin. Instead, pat it dry so as to not be too rough on it. Then be sure to add a moisturizer right away!
  • Take caution testing new products – If you’re trying out a new product, it’s best not to do a full treatment with it right off the bat. I recommend testing it on a small and discreet area of skin first.

If you have sensitive skin, I hope that these tips help you and your skin keep as healthy as possible!

If you’ve been dealing with sensitive skin and have some tips that I didn’t mention in this article, I’d love to hear them!

Just email info@everbella.com and share your tips with me. Maybe I’ll include them in a future post! 

Should Older Adults Take Collagen?

Collagen is the most abundant protein in the human body. It plays a role in the health of the skin, bones, cartilage, and more. 

Unfortunately, collagen depletes with age. It seems reasonable, then, that it would be important for us to be taking collagen as we get older. Right?

Right.

The reduction in collagen as we age leads to things like sagging skin and prominent wrinkles. On the inside, this decrease leads to weaker bones, which can be accompanied by a host of issues. [1]

Plenty of collagen studies have demonstrated positive results in bone and skin health during aging. [2, 3]

For example, one study in postmenopausal women with reduced bone mineral density found that a daily dose of collagen over the span of a year significantly increased bone mineral density of the femoral neck and spine, indicating reduced bone degradation and increased bone formation. [4]

A review of 11 collagen studies found that supplementing with the protein daily for six months improved hydration, elasticity, and collagen content of the skin. [5]

And a study from 2023 showed that collagen supplementation improved joint function and reduced pain, allong aging adults to be happier and more active! [6]

This makes sense when you remember that the cartilage within our joints is made up of collagen, and as our collagen levels decline, so will this important tissue within our joints.

What Are The Cons?

Honestly, I couldn’t find any!

Unlike questionable fads and trends that come and go, collagen is tried and true. After all, your body is full of this protein, needs it, but is losing it. 

I did find another pro, though!

Taking collagen can help boost your protein intake! You know, because it’s a protein. And studies have shown that increasing protein intake can help reduce age-related muscle loss and boost muscle function. [7]

If there is a con, it’s that most collagen supplements on the market aren’t bioavailable. Meaning your body can’t absorb it.

And you don’t get the benefits.

That’s why I use EverBella’s Micelle Liposomal Complete Collagen Plus.

Not only does it contain other ingredients – like MCT, algal DHA, and vitamin E – it’s infused with a micelle liposomal formula for superb absorption.

That means you can actually notice a difference.

>> Just click here to see how it has helped me and so many others!

References And Resources

  1. https://www.jbc.org/article/S0021-9258(20)44777-5/fulltext 
  2. https://www.scielo.br/j/rbgg/a/fk95TfhxB7mPsmqYRDdHH8K/?lang=en 
  3. https://pubmed.ncbi.nlm.nih.gov/25314004/ 
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793325/ 
  5. https://pubmed.ncbi.nlm.nih.gov/30681787/ 
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411303/
  7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924200/

Omega-3 vs Omega-6 Fatty Acids

The typical Western diet tends to present some challenges to our health and wellness. On one hand, it’s high in the food groups that should be kept in moderation, like red meat, processed foods, and high sugar foods. On the other hand, it’s low in the nutrients that we should get lots of, like fiber, water, certain vitamins and minerals, and essential fatty acids. Consequently, this diet style is associated with some negative outcomes if left unchecked, such as increased risk of heart disease, diabetes, obesity, and certain types of cancer. [1] 

Of all the nutrients that the Western diet tends to lack, omega-3 fatty acids seem to be among the hardest to get, despite their incredible benefits. This type of essential fatty acid is so important due to its impact on heart health, inflammation, skin health, and more. All the while, it can be incredibly challenging to get from our diet. Well, unless you know where to look for it…

While omega-3 fatty acids can be lacking in the Western diet, omega-6 fatty acids are usually found in abundance. While omega-6 fatty acids do have their benefits, they also have their drawbacks on human health as well. Interestingly enough, the most important factor to consider is the proportion of omega-6 fatty acids you eat in relation to omega-3 fatty acids. 

In this blog, I want to help you better understand what exactly the essential fatty acids are, and how they impact our health. I also want to help you identify common sources of these nutrients in the foods you eat, as well as the ideal ratio of omega fatty acids, so you can optimize your diet to support a healthy lifestyle. 

Omega-3 Fatty Acids

Omega-3 fatty acids are essential fatty acids, meaning that our body cannot produce these nutrients, and we must get them from our diet or supplements to maintain our stores. There are three main types of omega-3s – eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and alpha-linolenic (ALA).

They provide us with some incredible benefits, ranging from the health of our eyes, to our brains, to our hearts. Here are some of the most well-established benefits of omega-3s, according to research:

  • Consumption of these fats are known to play an important role in heart health. Studies have shown that eating omega-3s is associated with decreased triglycerides, improvement in healthy cholesterol, reduced risk of cardiovascular death, and reduced risk of cardiovascular incidents, like heart attacks. [2-5]
  • DHA is an essential component of your eyes, and plays a large role in ocular health. In fact, some studies have found that low intake of omega-3s may cause problems with vision, such as macular degeneration [6-7]
  • DHA is also an important component of your brain, especially in the development of the brain. Omega-3s are vital for the development of a fetus, and thus, are often included in prenatal vitamin supplements! [8]
  • There have also been studies to suggest that omega-3 fatty acids contribute to decreasing chronic inflammation in the body, as well as anxiety. [9]

You can find EPA and DHA in cold water, fatty fish, such as mackerel, tuna, salmon, herring, and shellfish. You can also find these fatty acids in vegetarian sources, as well. Primarily seaweed, nori, spirulina, and chlorella. ALA is more commonly found in plant-based sources, such as chia seeds, flax seeds, hemp seeds, walnuts, edamame, and kidney beans.

Omega-6 Fatty Acids

Like omega-3 fatty acids, omega-6 fatty acids are essential for our health, and we need to consume them on a regular basis. However, unlike omega-3 fatty acids, omega-6s tend to have some less desirable health effects when eaten in excess. 

Most significantly, researchers believe that they contribute to inflammation in the body. While inflammation can be good for us (it’s our body’s way of protecting us from illness and injury), too much inflammation can have some negative consequences. When inflammation persists, the cells and molecules that responded to the initial trigger can actually harm the body tissues they’re trying to protect. This is why we have to consider the amount of omega-6 fatty acids we eat, especially compared to omega-3 fatty acids (which have the opposite effect). [10]

Our diet is much more rich in omega-6 compared to omega-3. You can find omega-6s in a variety of vegetable oils, such as sunflower, safflower, soy, sesame, and corn oils, as well as in seeds and nuts. 

The Perfect Ratio for Optimized Health

While omega-6 fatty acids don’t seem to have the overwhelming benefits of omega-3s, together, they are essential for human health. In order to prevent the more negative outcomes associated with omega-6s, it’s important to maintain a healthy ratio of omega-3 to -6 intake. 

Currently, the Western diet style averages a ratio of 16:1, omega-6 to omega-3 fatty acids. In comparison, researchers suggest aiming for a ratio closer to 4:1 – i.e. for every 4 mg of omega-6 you consume, you should consume at least 1 mg of omega-3. This ratio would likely improve if the Western diet was richer in consumption of fatty fish, seaweed, algae, seeds, and nuts. However, it can be challenging to maintain consistent intake of these food groups. [11]

The good news is that supplementation is a great way to ensure that you’re getting enough omega-3 fatty acids on a daily basis. One of the more challenging forms of omega-3 to get is DHA, as many individuals may not regularly consume the fish or algae products that are rich in this nutrient. 

This is why I choose to formulate Complete Collagen+ with omega-3 fatty acids, DHA fatty acids in particular! I want to make sure that you’re getting all the power of collagen, with the added benefit of a daily dose of omega-3 fatty acids. EverBella’s collagen contains 400 mg of vegan DHA, and was designed to ensure that the collagen is more readily available for absorption. 

Try it, risk free with our 180-day, money back guarantee!

Citations

  1. Tilman, D., Clark, M. Global diets link environmental sustainability and human health. Nature 515, 518–522 (2014). https://doi.org/10.1038/nature13959
  2. Stone NJ.Fish consumption, fish oil, lipids, and coronary heart disease. Circulation. 1996; 94:2337–2340. CrossrefMedlineGoogle Scholar
  3. Hu FB, Bronner L, Willett WC, Stampfer MJ, Rexrode KM, Albert CM, Hunter D, Manson JE.Fish and omega-3 fatty acid intake and risk of coronary heart disease in women. JAMA. 2002; 287:1815–1821. CrossrefMedlineGoogle Scholar
  4. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto miocardico.Lancet. 1999; 354:447–455. CrossrefMedlineGoogle Scholar
  5. Kris-Etherton PM, Harris WS, Appel LJ; American Heart Association. Nutrition Committee. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation. 2002; 106:2747–2757. LinkGoogle Scholar
  6. SanGiovanni, John Paul, and Emily Y Chew. “The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina.” Progress in retinal and eye research vol. 24,1 (2005): 87-138. doi:10.1016/j.preteyeres.2004.06.002
  7. Merle, Bénédicte M J et al. “Circulating omega-3 Fatty acids and neovascular age-related macular degeneration.” Investigative ophthalmology & visual science vol. 55,3 2010-9. 28 Mar. 2014, doi:10.1167/iovs.14-13916
  8. Coletta, Jaclyn M et al. “Omega-3 Fatty acids and pregnancy.” Reviews in obstetrics & gynecology vol. 3,4 (2010): 163-71.
  9. Kiecolt-Glaser, Janice K et al. “Omega-3 supplementation lowers inflammation and anxiety in medical students: a randomized controlled trial.” Brain, behavior, and immunity vol. 25,8 (2011): 1725-34. doi:10.1016/j.bbi.2011.07.229
  10. Calder, Philip C. “n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases.” The American journal of clinical nutrition vol. 83,6 Suppl (2006): 1505S-1519S. doi:10.1093/ajcn/83.6.1505S
  11. A.P. Simopoulos. Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: nutritional implications for chronic diseases. Biomedicine & Pharmacotherapy, Volume 60, Issue 9, 2006, Pages 502-507, ISSN 0753-3322. https://doi.org/10.1016/j.biopha.2006.07.080